Chapter 7.3 · Where illness keeps company
Multiple chronic conditions
Weighted by adults, census tracts in the most deprived tenth were high on 5.7 of nine modeled chronic-condition prevalences on average in 2022, against 0.5 in the least deprived tenth, a count for tracts and not people.
Of the 82,78182,781 tractsEstimandcount of tractsWeightsnone (full count)Populationcensus tracts with an estimate for all nine conditions and an ADI rankPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023; ACS 2019-2023SourceCDC PLACES census tractsCensus tractA small area drawn by the Census Bureau to stand in for a neighborhood. Boundaries are redrawn after each decennial census. in the data for 2022, 892892 tractsEstimandcount of tracts that are high on all nine conditionsWeightsnone (full count)Populationcensus tracts with an estimate for all nine conditions and an ADI rankPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES were in the highest 25%25% percent of tractsEstimanddefinition: a tract is high on a condition when its prevalence is in the highest 25% of tracts, ties at their mean rankWeightsnone (a definition)Populationcensus tracts with an estimate for all nine conditions and an ADI rankPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES of tracts on the modeled prevalence among adults of each of nine chronic conditions. The nine are arthritis, cancer, current asthma, coronary heart disease, COPD, depression, diagnosed diabetes, obesity and stroke. If the conditions were unrelated across tracts, with each condition's observed share of high tracts, they would give 0.30.3 tractsEstimandnumber of tracts expected to be high on all nine conditions if they were independent across tracts (Poisson-binomial with the observed share high on each)Weightsnone (a benchmark)Populationcensus tracts with an estimate for all nine conditions and an ADI rankPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES tracts high on all nine. That benchmark is a reference point, and real tracts are not independent draws, in part because the model fits every condition to the same inputs. The count describes places. A tract can be high on several conditions while no resident has more than one, so the count says nothing about how many conditions any one person has.
The count rises at every step of the deprivation index
The chapter ranks tracts on the Area Deprivation IndexArea Deprivation Index (ADI)A score that ranks neighborhoods by income, education, employment and housing conditions drawn from the American Community Survey. In this book a higher national percentile means a more deprived neighborhood. (ADI), a national percentile built from American Community Survey (ACS) data. Weighted by adults, a tract in the most deprived tenth of tracts is high on 5.75.7 conditions (of nine)Estimandmean number of the nine conditions that are high, population-weighted mean over a tenth of tracts, bootstrap interval over countiesInterval95% CI 5.5 to 5.8n8,213 tractsWeightsadult population of the tract (PLACES)Populationadults in the most deprived tenth of tracts by ADI national percentilePeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES of the nine conditions on average, against 0.50.5 conditions (of nine)Estimandmean number of the nine conditions that are high, population-weighted mean over a tenth of tracts, bootstrap interval over countiesInterval95% CI 0.4 to 0.6n8,274 tractsWeightsadult population of the tract (PLACES)Populationadults in the least deprived tenth of tracts by ADI national percentilePeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES in the least deprived tenth. The mean count rises at every step from the least deprived tenth to the most deprived, with the two largest steps at the deprived end.
Part of this gradient is mechanical. The ADI is built from ACS data, and the PLACES model applies survey responses to each tract's census population using inputs from the same census sources. The conditions and the index therefore move together partly by design. The gradient of each condition taken one at a time belongs to Chapter 7.1, Health behaviors and the supply of care. The count here adds only that the conditions which rise are high in the same tracts.
Figure 1
Weighted by adults, a tract in the most deprived tenth is high on 5.7 of nine conditions on average, against 0.5 in the least deprived tenth
Population-weighted mean number of the nine conditions that are high, by tenth of tracts on the ADI national percentile, 82,781 tracts, 2022
Mean number of high conditions (of nine)
Show data
| conf_high | conf_low | decile | estimate | measure | n_units |
|---|---|---|---|---|---|
| 0.550 | 0.380 | 1 | 0.450 | count | 8,274 |
| 0.700 | 0.550 | 2 | 0.620 | count | 8,118 |
| 1 | 0.780 | 3 | 0.880 | count | 8,511 |
| 1.10 | 0.920 | 4 | 1.01 | count | 8,261 |
| 1.39 | 1.19 | 5 | 1.29 | count | 8,189 |
| 1.83 | 1.60 | 6 | 1.71 | count | 8,318 |
| 2.46 | 2.22 | 7 | 2.34 | count | 8,305 |
| 3.34 | 3.07 | 8 | 3.21 | count | 8,238 |
| 4.49 | 4.21 | 9 | 4.35 | count | 8,354 |
| 5.81 | 5.52 | 10 | 5.66 | count | 8,213 |
The line rises at every step from the least deprived tenth to the most deprived, and the last two steps are the largest. Each point is the mean number of high conditions in a tenth of tracts on the ADI, weighted by adults, with a 95% interval from a bootstrap over counties. The second view plots the share of adults living in tracts that are high on 55 conditionsEstimanddefinition: five or more of the nine conditions, a majorityWeightsnone (a definition)Populationcensus tracts with an estimate for all nine conditions and an ADI rankPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES or more of the nine. Values in Table 5.
Modeled estimates for tracts, not records of people
The prevalences are modeled estimatesModeled estimateA figure produced by a statistical model instead of a direct count or measurement, usually for small areas where direct data are thin, borrowing strength from surveys, neighboring areas or other data. Neighboring areas can share errors, so single extremes call for caution. from CDC PLACES, whose 2024 release uses survey responses from 2022.[1] PLACES fits a model to survey responses and applies it to the census population of each tract. It gives each tract one prevalence for each condition among adults and holds no record of any person. A tract is high on a condition when its prevalence is in the highest 25%25% percent of tractsEstimanddefinition: a tract is high on a condition when its prevalence is in the highest 25% of tracts, ties at their mean rankWeightsnone (a definition)Populationcensus tracts with an estimate for all nine conditions and an ADI rankPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES of tracts, with each tract counted once. A tract's count is the number of the nine conditions on which it is high. High blood pressure and high cholesterol are left out because the 2024 release has no tract estimate of either for Florida. Means and correlations are population-weightedPopulation-weightedAveraged so that each place counts in proportion to its number of residents, which lets a large county move the result more than a small one. An unweighted average counts every place equally., so each tract counts in proportion to its adult residents. In surveys that ask each adult about each condition, multiple chronic conditions means one person having more than one of them,[2] and a tract estimate cannot be turned into that count. A tract can be high on none of the nine while some of its residents have several. The report gives every estimate with its interval and sample size.
The overlap is smaller inside the most deprived tenth
Across all tracts, the average correlation between the prevalences of two of the nine conditions is +0.49 (95% CI 0.48 to 0.51)+0.49 correlation coefficient (mean of the 36 pairs)Estimandmean of the population-weighted Pearson correlations over the 36 pairs of conditions, bootstrap interval over countiesInterval95% CI 0.48 to 0.51n82,781 tractsWeightsadult population of the tract (PLACES)Populationadults living in census tracts with an estimate for all nine conditions and an ADI rankPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES. A positive correlation means that tracts high on one condition tend to be high on the other. The conditions do not go together more closely where deprivation is higher. Inside the least deprived tenth of tracts the mean correlation among the nine is +0.40+0.40 correlation coefficient (mean of the 36 pairs)Estimandmean pairwise correlation among the nine conditions inside one tenth of tracts, bootstrap interval over countiesInterval95% CI 0.37 to 0.44n8,274 tractsWeightsadult population of the tract (PLACES)Populationadults in the least deprived tenth of tractsPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES, and inside the most deprived tenth it is +0.34+0.34 correlation coefficient (mean of the 36 pairs)Estimandmean pairwise correlation among the nine conditions inside one tenth of tracts, bootstrap interval over countiesInterval95% CI 0.32 to 0.36n8,213 tractsWeightsadult population of the tract (PLACES)Populationadults in the most deprived tenth of tractsPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023SourceCDC PLACES. The count of high conditions rises with deprivation, while the overlap among the conditions inside a tenth is smaller in the most deprived tenth than in the least deprived.
Approximating the census inputs leaves most of the overlap
Part of every correlation among the PLACES estimates is built into the estimates. The model uses the age, sex, race, ethnicity and education of each survey respondent, a county measure of poverty, and state and county effects. Conditions that are modeled from the same inputs move together wherever the inputs move, whatever the residents do.
The data cannot take the model apart, but the ACS can approximate its inputs. For each condition, a weighted regression on census shares of tract residents by age, race, ethnicity and schooling, with a county poverty rate and state effects, approximates those inputs. It reproduces 79%79% percent of the variance of tract prevalenceEstimandsmallest weighted R squared of the nine fits on the ACS shares, county poverty and state effectsn82,578 tractsWeightsadult population of the tract (PLACES)Populationadults living in census tracts with an estimate for all nine conditions and an ADI rank and every ACS input of the approximationPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023; ACS 2019-2023SourceCDC PLACES to 90%90% percent of the variance of tract prevalenceEstimandlargest weighted R squared of the nine fits on the ACS shares, county poverty and state effectsn82,578 tractsWeightsadult population of the tract (PLACES)Populationadults living in census tracts with an estimate for all nine conditions and an ADI rank and every ACS input of the approximationPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023; ACS 2019-2023SourceCDC PLACES of the variance of tract prevalence, counting the part the state effects carry. The fit leaves out the tracts that lack a census share, among them the tracts of the District of Columbia. On the tracts it keeps, the average correlation is +0.49 (95% CI 0.48 to 0.51)+0.49 correlation coefficient (mean of the 36 pairs)Estimandmean pairwise correlation among the nine conditions on the tracts the approximation uses, bootstrap interval over countiesInterval95% CI 0.48 to 0.51n82,578 tractsWeightsadult population of the tract (PLACES)Populationadults living in census tracts with an estimate for all nine conditions and an ADI rank and every ACS input of the approximationPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023; ACS 2019-2023SourceCDC PLACES for the conditions themselves and +0.47 (95% CI 0.46 to 0.48)+0.47 correlation coefficient (mean of the 36 pairs)Estimandmean pairwise correlation among the nine conditions after removing a fit on eight ACS tract shares, the county poverty rate and state effects; the fit is not refitted inside the bootstrap, so the interval conditions on itInterval95% CI 0.46 to 0.48n82,578 tractsWeightsadult population of the tract (PLACES)Populationadults living in census tracts with an estimate for all nine conditions and an ADI rank and every ACS input of the approximationPeriodBRFSS 2022 (PLACES 2024 release); ADI 2023; ACS 2019-2023SourceCDC PLACES for what the fit leaves unexplained (Figure 2).
Figure 2
An approximation of the model's census inputs leaves the average correlation among the nine conditions at +0.47, against +0.49 in the raw data
Mean of the 36 pairwise population-weighted correlations among the nine conditions across 82,781 tracts, 2022, under seven comparisons
- Compared within groups of tracts
- After approximating the model's inputs
Show data
| conf_high | conf_low | estimate | group | n | stage |
|---|---|---|---|---|---|
| 0.511 | 0.477 | 0.495 | Compared within groups of tracts | 82,781 | All tracts |
| 0.498 | 0.471 | 0.484 | Compared within groups of tracts | 82,781 | Within states |
| 0.435 | 0.418 | 0.427 | Compared within groups of tracts | 82,781 | Within counties |
| 0.377 | 0.346 | 0.361 | Compared within groups of tracts | 82,781 | Within tenths of the ADI |
| 0.476 | 0.460 | 0.468 | After approximating the model's inputs | 82,578 | Census shares, county poverty and state effects removed |
| 0.521 | 0.511 | 0.516 | After approximating the model's inputs | 82,578 | Census shares removed within counties |
| 0.469 | 0.441 | 0.455 | After approximating the model's inputs | 82,578 | Flexible fit (trees) on the same inputs and state |
All seven dots stay right of zero, and the three rows that remove an approximation of the model's inputs lie close to the raw value. Each dot is the mean of the pairwise correlations among the nine conditions after the stated step, with a 95% interval from a bootstrap over counties that does not refit the adjustment. The row for all tracts and the three adjusted rows are drawn in colour, and the other rows compare tracts within states, counties and tenths of the ADI. The fits are an approximation of the PLACES model and not the model. Values in Table 6.
These numbers show that the inputs which can be measured here do not remove the overlap. They do not show that the overlap is real. The fits approximate the model and are not the model. The ACS file has no sex shares, and the model works from individual respondents and not tract shares. Whatever the conditions share and the fit misses stays in what is left unexplained and keeps it correlated. The data cannot say how much of the shared part comes from the model's other inputs and how much from the neighborhoods.
A check from death records
Death records give a check that does not depend on the PLACES model. USALEEPUSALEEPThe U.S. Small-area Life Expectancy Estimates Project, a National Center for Health Statistics release of life expectancy at birth for most census tracts. It covers deaths from 2010 to 2015 only and has not been updated. life expectancy at birthLife expectancy at birthThe average number of years a newborn would live if death rates at every age stayed as they were in the period measured. It summarizes the death rates of a period and is not a forecast for any child., built from deaths in 2010 to 2015, is 6.1 (95% CI 5.8 to 6.3)6.1 years of life expectancy at birthEstimanddifference in population-weighted mean tract life expectancy, bootstrap interval over counties (draws shared)Interval95% CI 5.8 to 6.3n29,329 tractsWeightsACS 2019-2023 tract populationPopulationresidents of tracts that are high on none of the nine conditions compared with tracts that are high on eightPerioddeaths in 2010 to 2015 (USALEEP, area-weighted onto 2020 tracts); PLACES 2024 releaseSourceUSALEEP life expectancy years shorter in tracts that are high on eight of the nine conditions than in tracts that are high on none. Life expectancy at birth is built from death rates at each age, so the age mix of a tract does not move it the way it moves crude prevalence. That makes it a check on whether the count reflects more than age. Tracts that are high on all nine have a longer life expectancy than tracts that are high on eight, and the data here do not say why.
Figure 3
Life expectancy at birth is 6.1 years shorter in tracts that are high on eight conditions than in tracts that are high on none
Population-weighted mean tract life expectancy at birth by number of high conditions, 77,934 tracts, deaths in 2010 to 2015, institutional tracts dropped
Show data
| conf_high | conf_low | count | estimate | measure | n_units |
|---|---|---|---|---|---|
| 80.37 | 79.98 | 0 | 80.18 | level | 26,431 |
| 80 | 79.64 | 1 | 79.82 | level | 15,948 |
| 78.50 | 78.18 | 2 | 78.33 | level | 8,632 |
| 78.19 | 77.78 | 3 | 77.97 | level | 5,599 |
| 77.32 | 76.79 | 4 | 77.06 | level | 4,541 |
| 76.72 | 76.18 | 5 | 76.45 | level | 4,162 |
| 76.38 | 75.96 | 6 | 76.16 | level | 4,602 |
| 74.84 | 74.35 | 7 | 74.59 | level | 4,248 |
| 74.30 | 73.94 | 8 | 74.12 | level | 2,898 |
| 75.41 | 74.93 | 9 | 75.17 | level | 873 |
The line falls from the tracts where no condition is high to the tracts where eight are high, and ends higher at nine. Each point is the mean tract life expectancy at birth for tracts with that number of high conditions, weighted by population, with a 95% interval. Life expectancy comes from death records for 2010 to 2015 and the count from the 2022 PLACES estimates. The second view subtracts each tract's county mean to compare tracts within counties. Values in Table 8.
Within a county the count varies only through the composition of tract residents, which also moves life expectancy, so the comparison within counties does not isolate the conditions. The two sources cover different years, 2010 to 2015 and 2022, and a correlation between them does not show that the conditions shorten lives. Pooled over tracts, the count of high conditions in the 2022 PLACES estimates rises with deprivation and goes with shorter life expectancy in the death records of 2010 to 2015. These are descriptions of places, and a count among tracts is not any resident's risk.
What this cannot tell you
No figure here says how many conditions an adult has, and reading the tract overlap as people with several conditions at once is ecological inferenceEcological inferenceDrawing conclusions about individuals from data about places or groups. A pattern across counties need not hold for the people inside them.. The tract file has no intervals, so the bands describe the sampling of counties and not the model's own uncertainty. Values are crude prevalence among adults, so the age of a tract's residents is part of every pattern. A tract that is high on a condition is high compared with other tracts and not by any clinical standard, and the cutoff moves every count.
Go deeper
- The report: every estimate with its interval and sample size.
- Tables: every figure of the report as a table.
Data sources
- CDC PLACESCDC PLACES 2024 release, census tracts, crude prevalence among adults of nine conditions (BRFSS 2022)Years: 2024 release (tracts); 2025 release (ZCTAs, 2023 data year) · Weights: adult population of the tract · License: Public domain (CDC, U.S. Department of Health and Human Services)
- Area Deprivation IndexNeighborhood Atlas Area Deprivation Index, 2023, national percentileYears: 2023 release (version 4.0.1; built on ACS 2019-2023) · Weights: adult population of the tract · License: Free for non-commercial use; cite the Neighborhood Atlas and Kind and Buckingham
- American Community SurveyACS 2019-2023 tract shares used to approximate the model's inputsYears: 2019-2023 (5-year) · Weights: adult population of the tract · License: Public domain (U.S. Census Bureau)
- USALEEP life expectancyNCHS small-area life expectancy at birth, 2010-2015, 2020 tractsYears: 2010-2015 · Weights: ACS 2019-2023 tract population · License: Public domain (NCHS, CDC)
- Published estimates from cited studiesEstimates quoted in the causal box (Ludwig and coauthors 2011)Years: as reported in each study · Weights: as reported in the study · License: Quoted from published research for commentary
References
- Greenlund, Kurt J.; Lu, Hua; Wang, Yan; Matthews, Kevin A.; LeClercq, Jennifer M.; Lee, Benjamin; Carlson, Susan A. (2022). PLACES: Local Data for Better Health. Preventing Chronic Disease 19: 210459. doi:10.5888/pcd19.210459
- Ward, Brian W.; Schiller, Jeannine S. (2013). Prevalence of Multiple Chronic Conditions Among US Adults: Estimates From the National Health Interview Survey, 2010. Preventing Chronic Disease 10: 120203. doi:10.5888/pcd10.120203
How to cite
@misc{singh2026multiplechronicconditions,
author = {Singh, Vishal},
title = {Multiple chronic conditions},
year = {2026},
url = {https://vishalsingh.org/zipcode/multiple-chronic-conditions},
note = {In ZIP Code Destiny. Published 9 October 2026.}
}